G6PD deficiency is an inherited condition, usually affecting baby boys (25% Chinese and Malay), where the body has insufficient glucose- 6-phosphate dehydrogenase (G6PD) enzymes. In this condition, the red blood cells may break down and cause jaundice and anaemia. All newborns are screened for G6PD deficiency by their cord blood.
If your newborn is diagnosed with G6PD deficiency, the doctor will counsel you about the condition and the precautions to take for your baby.
Your baby will need to remain in hospital for at least 72 hours after birth for monitoring and possibly treatment of jaundice. After hospital discharge, take care of your newborn as usual.
However, always check with your healthcare professional before taking any medication. Be careful about using herbal supplements or alternative therapies.
In particular, the items below must be avoided life long. Mothers who are breastfeeding must also avoid the food and drugs on this list.
Antibiotics
Antimalarials
Chemicals
Food
Signs & Symptoms
Some newborns with G6PD deficiency may develop jaundice more easily during the first week of life. Decades ago in Singapore, before screening of G6PD deficiency was done routinely, some affected newborns developed high levels of jaundice which caused brain injury.
About the condition
Most people with G6PD deficiency have a completely normal life as long as they avoid certain foods and drugs and environmental chemicals.
Reference: Healthhub, National University Hospital
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